Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular ...

This article explores how challenges such as sequence optimization, immune activation and off-target effects are being ...

From enzymes and lipid nanoparticles to large-scale process design, four global innovators redefine RNA-based medicine development and delivery.

Cells frequently encounter conditions that can damage them or even lead to cell death. To keep functioning, they must rapidly ...

Researchers have found a small but powerful switch inside breast cancer cells that helps them survive stressful conditions.

It was 2012 when Love Dalén, a paleogeneticist at Stockholm University, first laid eyes upon a special specimen on a lab table in eastern Siberia. "Our Russian collaborators said, 'Come here into this ...

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs). As the most abundant internal modification of ...

Scientists have sequenced the oldest-ever RNA from a 39,000-year-old woolly mammoth named Yuka, whose remains were found frozen on a bluff in northeastern Siberia. The discovery contradicts the ...

In 2010 Yukaghir hunters found the nearly intact carcass of a young woolly mammoth frozen in the northern Siberian permafrost. With its reddish-brown fur still clinging to its skin, the dog-sized calf ...

Researchers from the University of Eastern Finland and Aalto University have developed a computational framework called SegPore that enhances the accuracy of RNA modification detection from direct RNA ...

N6-methyladenosine (m6A) is the most prevalent internal modification of eukaryotic mRNA and has emerged as a pivotal regulator of gene expression at the post-transcriptional level. In the tumor immune ...

This study is led by Professor XiaoqinLiu (Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agriculture Sciences, Shangdong, China). The authors explored ...