Kickoff from U.S. Bank Stadium in Minneapolis is set for 4:30 p.m. ET. The latest Vikings vs. Lions odds have Detroit favored by 7.5 points, while the over/under for total points scored is 43.5 via DraftKings Sportsbook. Before making any Lions vs. Vikings picks, check out the NFL predictions from the SportsLine Projection Model .

Learn which TV channel or how to live stream the NFL Week 17 Minnesota Vikings and Detroit Lions game, Thursday, Dec. 25.

Detroit Lions quarterback Jared Goff (16) makes a pass against Dallas Cowboys during the second half at Ford Field in Detroit on Thursday, Dec. 4, 2025. The Lions have alternated wins and losses over their past eight games (4-4). The Lions won't play until ...

The Lions are on the outside of the NFC playoff picture entering Week 16. Here's a look at their playoff chances and scenarios.

The Green Bay Packers and Minnesota Vikings have a historic matchup waiting in the 129th edition of the rivalry on Sunday afternoon from U.S. Bank Stadium in Minneapolis. Never before have the two teams had more combined wins entering a matchup.

Pregame analysis and predictions of the Detroit Lions vs. Minnesota Vikings NFL game to be played on December 25, 2025 on ESPN.

All-Pro safety Kerby Joseph will miss his ninth straight game Sunday, Dec. 19, against the Pittsburgh Steelers because of a knee injury. Joseph has not played since an Oct. 12 loss to the Kansas City Chiefs because of a chronic knee issue but remains on the Detroit Lions ' 53-man roster.