NFL Week 16 picks, odds, best bets
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3 best NFL bets for week 16 (2025)
We’re headed to Week 16 of the NFL season, and I’ve added the three best NFL bets using our premium betting systems. Some of these systems have been printing money all year. That said, let’s get right to it.
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No touchdowns from Nacua, but he had a massive game nonetheless — nine catches for 181 yards on just 11 targets, averaging better than 20 yards per reception. This matches the most catches in a game this season while still averaging 20 yards per catch or better — the Eagles' DeVonta Smith went nine for 183 in a Week 7 win over the Vikings.
It's getting down to crunch time for NFL teams looking to make the playoffs, and the landscape of the NFC race saw a major shift on Thursday
You can also see the model's best bets for every Week 16 NFL game. Finally, SportsLine expert Bruce Marshall, who is 46-26-2 (+1695) over his last 74 NFL ATS picks, has locked in multiple Week 16 NFL picks. Visit SportsLine to see his best bets.
The Iowa State Cyclones are losing a lot of talented players from their 2025 roster. With Jimmy Rogers taking over as head coach from Matt Campbell, there is a
There are big games and bigger stakes on the 15th Sunday of this NFL season. Those results should rearrange and clarify the playoff picture.
Best NFL players ever on the worst teams: Myles Garrett, Calvin Johnson and the 16 most wasted talents in history originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here. Cleveland edge rusher Myles Garrett is on the edge of making NFL history.
According to ESPN Research, the Bengals have a strong chance at a top 10 spot: “What's at stake: Both teams have been eliminated from playoff contention. The Bengals have 62% chance to land a top-10 pick in the draft, and the Dolphins have a 55% chance, according to ESPN Analytics.”
With three weeks left in the NFL season, the No. 1 overall pick is up in the air and teams are well on their way to getting clarity on what their biggest needs will be in April.
Sports bettors can register with the bet365 bonus code SBKWIRE and get $150 in bonus bets. Wager on the Bears vs the Packers, NFL Week 16 games today.