Proteolysis describes the breakdown of proteins into smaller units, such as polypeptides or amino acids. Image Credit: Juan Gaertner/Shutterstock.com It is a vital process in humans and animals that ...
In 2001, chemists K. Barry Sharpless, Hartmuth C. Kolb, and M. G. Finn introduced click chemistry, a concept in which organic ...
We show here that pulse proteolysis is capable of quantitatively determining protein stability with minimal instrumentation in crude lysates without purification. We also demonstrate the method's ...
How the genetic code is translated into proteins was a key focus of biological research before the 1980s, but how these proteins are degraded remained a neglected area. With the discovery of the ...
It is widely assumed that mitotic cyclins are rapidly degraded during anaphase, leading to the inactivation of the cell cycle-dependent protein kinase Cdc2 and allowing exit from mitosis. The ...
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Next-gen flu vaccines use proteolysis-targeting to boost safety and cross-strain immunity in animal models
Recently, Prof. Si Longlong's team from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences constructed a library of live-attenuated influenza A vaccines that utilize ...
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