Besides building a cell's protein factories, this specialized subunit, or the nucleolus, serves more broadly as a control center for cellular growth and health. Only recently has the nucleolus gotten ...

Although known since the 1830s as a round, dark spot in a cell's nucleus, only recently has the nucleolus gotten its full due. Scientists have learned that besides building a cell's protein factories, ...

Deep within the nucleus of every cell lies a structure smaller than a pinpoint that may hold the secret to aging. Scientists at Weill Cornell Medicine have discovered that the nucleolus, long known ...

New research has advanced understanding of how the nucleolus is assembled through a process called liquid-liquid phase separation and has identified a protein that plays key role Researchers have ...

The nucleolus—a conspicuous but obscure organelle within the cell nucleus—is normally too compact to be studied in detail. Researchers at Case Western Reserve University just learned how to simplify ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

This model of the nucleus with nucleolus (pink) shows how ribosomal DNA is correctly repaired in young cells. In old cells with enlarged nucleolus, however, DNA repair is inaccurate leading to faster ...

Keeping nucleoli small prevents DNA instability and cellular aging, akin to anti-aging effects like calorie restriction Nucleolar expansion marks a tipping point in aging, acting as a "mortality meter ...

Chinese scientists have made a fundamental breakthrough in the understanding of the nucleolus, a structure with important functions in the nucleus. Their findings may also pave the way for diagnoses ...