Narcolepsy is caused by a deficiency of orexin, a brain chemical that regulates wakefulness and REM sleep. The MSLT and polysomnography are gold standards for diagnosing narcolepsy. Medications like ...

Type 1 narcolepsy is often more severe and includes cataplexy, which is sudden muscle weakness triggered by emotions. Both type 1 and type 2 narcolepsy cause excessive daytime sleepiness, but people ...

Alkermes' alixorexton has become the first drug in the orexin 2 receptor agonist class to show efficacy in phase 2 trials involving patients with both main subtypes of sleep disorder narcolepsy.

Brendon Yee, PhD, professor and respiratory and sleep physician, Woolcock Institute of Medical Research, discusses the success of ALKS 2680, an investigational oral selective orexin 2 receptor agonist ...

That overwhelming sleepiness dragging you down might not just be from staying up too late scrolling through TikTok. While everyone occasionally battles the afternoon slump, people with hypersomnia or ...

Oveporexton, a novel first-in-class OX2R-selective agonist, shows promise for improving memory, attention, and executive function in individuals with narcolepsy type 1.

A new study has demonstrated a new way to treat narcolepsy-related nightmares. The scientists combined cognitive behavioral therapy (CBT) and lucid dreaming to help patients in a small clinical trial.

Narcolepsy and idiopathic hypersomnia (IH) both lead to daytime sleepiness, fatigue, and brain fog. Narcolepsy can involve muscle weakness and sleep paralysis, while IH may lead to non-refreshing ...

Narcolepsy may stem from the lack of the neurotransmitter hypocretin. It is a long-term neurological condition that causes fragmented sleep, daytime sleepiness, brain fog, and other symptoms. It also ...

When Katelynn O’Connell takes her lunch break at work, she follows a routine that sets her apart from other employees. Each day at noon, she unfolds a cot in her small office, turns on a white noise ...

The late-night show host Jimmy Kimmel returns to the stage on Tuesday, after a suspension from ABC for commenting on the shooting of right-wing activist Charlie Kirk. What Happened To Jimmy Kimmel?