This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

In a recent study published in the journal Science Advances, a group of researchers investigated the role of histone modifications in human aging by developing and evaluating histone-specific age ...

Epigenetics plays a critical role in human health by regulating gene expression without the direct modification of DNA sequence. Aberrant epigenetic modifications mediated by changes in DNA and ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

The developmental period is a critical window during which environmental cues interact with the genome to shape lifelong trajectories of health and disease.

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(A) Global DNA hypomethylation contributes to genomic instability, while promoter hypermethylation leads to the silencing of tumour suppressor genes, promoting tumour progression. (B) HPTM writers, ...

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...