If a recent blood test shows elevated bilirubin levels, there’s a chance you could have a common and generally harmless genetic condition known as Gilbert Syndrome, which is pronounced “Jill-bear,” ...

Bilirubin, the primary breakdown product of hemoproteins, particularly hemoglobin, plays a key role in the diagnosis, prognosis, and monitoring of liver diseases. In acute liver diseases, such as ...

Bilirubin, a by-product of haem metabolism, plays a crucial role in human physiology beyond its well-known association with jaundice. Emerging evidence underscores its antioxidant and cell signalling ...

Introduction to Newborn Jaundice Parents often experience anxiety when their newborn is diagnosed with jaundice. Fortunately, ...

More than 15 years in the making, the revised AAP Clinical Practice Guideline Revision: Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation was released in 2022. A key ...

Patients with the Crigler–Najjar syndrome lack the enzyme uridine diphosphoglucuronate glucuronosyltransferase 1A1 (UGT1A1), the absence of which leads to severe unconjugated hyperbilirubinemia that ...

Approximately 1% of neonates born to O+, antibody-negative mothers qualified for phototherapy within 24 hours of birth, with most identified through routine bilirubin screening. The visual detection ...

High levels of bilirubin exacerbated damage to neurons in the brain caused by a stroke by binding to the TRPM2 channel, which helped regulate cell death among other processes. The research, led by ...

Findings presented at the American College of Cardiology Annual Scientific Session indicate that finerenone's efficacy in reducing cardiovascular death did not significantly differ across baseline ...

Jaundice is the yellowing of your skin and eyes caused by too much bilirubin in the blood, often from liver problems. You may notice some yellowish skin discoloration, but it can be harder to spot on ...

Gene therapy for Crigler-Najjar syndrome appeared promising in patients treated at a higher dose, a phase I/II trial showed. A single infusion of GNT0003 -- an adeno-associated virus serotype 8 vector ...