In Week 15 against the Tennessee Titans, the 49ers surrendered 14 points in the fourth quarter. In Week 11 against the Arizona Cardinals, they allowed 12 points in the final quarter. Against the New York Giants, San Francisco again gave up 14 fourth-quarter points but responded by scoring the same amount to secure the win.

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host Cardinals (3-7).

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale.

The Arizona Cardinals were beaten 41-22 by the San Francisco 49ers on Sunday at State Farm Stadium. A lot of thing went wrong. However, moving the ball offensively wasn't one of the problems. They had a season-high 488 yards of offense. They outgained the 49ers 488 to 281 in yards.

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are the highlights.

The Arizona Cardinals were destroyed by the Seahawks last week but they have a chance to get back on track in Week 11, with the 49ers coming to town.

The San Francisco 49ers entered their second matchup against the Arizona Cardinals as favorites and won. Here were the worst performers from the game.

It wasn't just the Seahawks celebrating Thursday's night win. The 49ers now have a path to the NFC West title, too.